If you’re searching for a natural way to increase your energy, boost mental clarity, and support metabolic health, the best B-complex and berberine supplements can offer exactly that. These supplements combine essential vitamins and plant-based compounds to help your body perform at its best. From delicious gummies to highly bioavailable liquid drops, our curated list includes only the best B-complex and berberine supplements available in 2025.
1. INTEGO NUTRITION – B-Complex Gummies for Adults
Overview
These gummies are specifically designed for adults looking for a pleasant and effective source of B vitamins. In fact, they are suitable for both men and women, and the gummy format makes it easy to incorporate into your daily routine. They are formulated to support brain health and provide a natural energy boost.
Key Ingredients
- B-complex vitamins
- Natural flavors
- Gluten-free, no artificial ingredients
Benefits
- Stimulate energy metabolism
- Enhance mental focus
- Support nervous system function
Pros
- Great taste
- Convenient to consume
- Good value for money
Cons
- Limited quantity (60 gummies)
- May contain added sugar
Rating: 4.5 out of 5 stars (1,268 reviews)
Price: $9.99 ($0.17 per gummy)
2. Vitafusion – B-Complex Gummies + Vitamin C
Overview
This gummy supplement offers a balanced mix of five B vitamins along with Vitamin C. Therefore, it’s ideal for those wanting to support cellular energy production and boost their immune system with a tasty product.
Key Ingredients
- Vitamins B1, B2, B3, B6, B12
- Vitamin C
- Natural strawberry flavor
Benefits
- Enhances cellular energy production
- Strengthens immune function
- Supports mental clarity
Pros
- Pleasant taste
- Easy to digest
Cons
- Only 60 gummies per bottle
- Lower content of B9 (folate)
Rating: 4.7 out of 5 stars (91 reviews)
Price: $10.98
3. Berberine HCL Liquid Drops – 1500 mg with Turmeric, Cinnamon, and Chromium
Overview
This liquid supplement offers a potent combination of active ingredients to support metabolism, immunity, and gut health. Moreover, the liquid form ensures high bioavailability and fast absorption.
Key Ingredients
- Berberine HCL (1500 mg)
- Turmeric
- Ceylon Cinnamon
- Chromium
- Niacinamide
Benefits
- Boosts metabolic function
- Improves insulin sensitivity
- Supports digestive and gut health
Pros
- High concentration of active ingredients
- Fast-absorbing liquid form
- Includes synergistic ingredients
Cons
- Strong taste
- Small bottle (2 oz)
Rating: 4.2 out of 5 stars (111 reviews)
Price: $14.99 ($7.50 per oz)
4. NEW AGE – B-Complex Gummies with Vitamin C, Biotin, and Folic Acid
Overview
These gummies are among the most complete options on the market, especially formulated for those on vegan and gluten-free diets. As a result, each bottle contains 120 units, offering longer use compared to other similar products.
Key Ingredients
- Vitamins B3, B5, B6, B7, B9, B12
- Biotin
- Folic Acid
- Vitamin C
Benefits
- Supports hair, skin, and nail health
- Enhances energy production
- Strengthens the immune system
Pros
- Vegan and gluten-free
- More comprehensive formula
- Large bottle size
Cons
- Higher price point
- Flavor may taste artificial to some
Rating: 4.6 out of 5 stars (1,295 reviews)
Price: $32.95 ($0.27 per gummy)
5. musebeam – Organic Berberine Liquid HCl (1000 mg)
Overview
This vegan supplement features an advanced formula of berberine combined with natural ingredients like turmeric and artichoke. Consequently, it is a clean, highly bioavailable option free from fillers and additives.
Key Ingredients
- Berberine HCl (1000 mg)
- Artichoke
- Turmeric
- Milk Thistle
- Ceylon Cinnamon
Benefits
- Regulates blood sugar levels
- Promotes liver and digestive health
- Supports natural detox processes
Pros
- Organic and vegan formula
- High bioavailability
Cons
- Only 24 reviews
- May require refrigeration
Rating: 4.4 out of 5 stars (24 reviews)
Price: $11.99 ($6.00 per oz)
6. Nature Made – Super B-Complex with Vitamin C and Folic Acid
Overview
One of the most popular and trusted options on the market, this tablet-based supplement offers a complete B-complex with Vitamin C and folic acid. Hence, it’s ideal for those who prefer tablets over gummies or liquids.
Key Ingredients
- Vitamins B1 to B12
- Vitamin C
- Folic Acid
Benefits
- Supports immune and energy functions
- Promotes cardiovascular and brain health
- Excellent value for the price
Pros
- Generous count (140 tablets)
- Competitive pricing
- Trusted brand
Cons
- Not suitable for strict vegans
- Not available in gummy form
Rating: 4.7 out of 5 stars (29,541 reviews)
Price: $9.69 (was $16.19)
7. Vegan B-Complex Gummies with Methyl B12, Choline, and Inositol
Overview
These premium gummies offer an advanced B-complex formula with activated methyl B12 and folate for better absorption. Additionally, they also include choline, inositol, Vitamin C, and zinc to support overall wellness.
Key Ingredients
- Methyl B12 (2000 mcg)
- Methyl Folate
- Choline
- Inositol
- Vitamin C and Zinc
Benefits
- Supports mood and cognitive function
- Enhances memory and focus
- Promotes cellular health
Pros
- Advanced, high-potency formula
- Ideal for those with specific deficiencies
Cons
- Higher cost
- Not always in stock
Rating: 4.6 out of 5 stars (282 reviews)
Price: $35.99
The best B-complex and berberine supplements are more than just daily vitamins—they’re powerful tools for supporting brain function, energy metabolism, and immune response. Whether you prefer tasty gummies or potent liquid formulas, the options we’ve reviewed here make it easy to find the best B-complex and berberine supplements for your lifestyle and health goals.
